Published January 1986
by Excerpta Medica .
Written in English
|Contributions||S. Yousuf Ali (Other Contributor)|
|The Physical Object|
|Number of Pages||424|
Extracellular vesicles (EVs) are lipid bilayer-delimited particles that are naturally released from a cell and, unlike a cell, cannot replicate. EVs range in diameter from near the size of the smallest physically possible unilamellar liposome (around nanometers) to as large as 10 microns or more, although the vast majority of EVs are smaller than nm. Impaired Calcification Around Matrix Vesicles of Growth Plate and Bone in Alkaline Phosphatase-Deficient Mice Article in American Journal Of Pathology (3) April with 52 Reads. Learning objectives: Vascular calcification is a regulated cell mediated process. Matrix vesicles are the nucleating factors in vascular calcification. Extracellular calcium acts to change the mineralization capacity of matrix vesicles. Matrix vesicles are of endosomal origin and are released as : Alexander Kapustin. ISBN: OCLC Number: Description: pages: illustrations ; 25 cm: Contents: Dynamics of calcium phosphate precipitation / E.D. Eanes --Role of collagen fibrils in calcification / E. Bonucci --Role of proteoglycans in calcification / N. Shepard --Role of lipids in osteogenesis: cell signaling and matrix calcification / R. Dziak --Role of matrix .
BOOK REVIEWS BOOK REVIEWS Book review in this article: Cell‐Mediated Calcification and Matrix Vesicles,. Edited by S. Yousuf All Elsevier Science Publishers B.V., Amsterdam, , pp. , $ However, more recent data suggest that cardiovascular calcification may encompass both passive (e.g., biochemical factors, circulating nucleating complexes) and active processes (e.g., cell-mediated processes involving cell death of macrophages and smooth muscle cells (SMCs), and/or the release of matrix vesicles by SMCs). Vascular calcification is highly prevalent in patients with coronary artery disease and, when present, is associated with major adverse cardiovascular events, including an increased risk of cardiovascular mortality. The pathogenesis of vascular calcification is complex and is now recognized to recapitulate skeletal bone formation. Vascular smooth muscle cells (SMC) play Cited by: Interestingly, the first step in calcification of cartilage, bones, and teeth in vertebrates takes place within membrane-bound vesicles, termed matrix vesicles (Anderson, ). Needle-like crystals of calcium phosphate initiate within these vesicles and provide centers for further proliferation of apatite (crystalline calcium phosphate).
This observation was supported by the finding that there are miRs that are commonly packaged in matrix vesicles across several different cell types. Analysis of the matrix vesicles and cellular miR content of HEKT, human microvascular endothelial cells and primary outgrowth endothelial progenitor cells revealed that miR, miR, miR Cited by: In Cell Mediated Calcification and Matrix Vesicles (ed. S. Y. Ali), Elsevier Bioscience BV, – Google Scholar Boyan-Salyers, B. D. (). In The Chemistry and Biology of Mineralized Connective Tissues (ed. A. Veis), Elsevier-North Holland, –42 Google ScholarCited by: This term is more specific than “mineralization,” as biologic mineralization implies a relation between the cells, the organic matrix, and the mineral. The cell-mediated biomineralization process comprises oriented deposition of mineral within or adjacent to cells or upon an extracellular matrix. The extracellular matrix (ECM) and secreted vesicles are unique structures outside of cells that carry out dynamic biological functions. ECM is created by most cell types and is responsible for the three-dimensional structure of the tissue or organ in which they are by: 8.